Prenatal follow-up
PGT does not replace prenatal screening or diagnostic options. Patients should receive counselling about residual risk and confirmatory testing where appropriate.
Preimplantation genetic testing
PGT-A
PGT-A assesses chromosome copy number in embryo biopsy material. Routine benefit for every IVF patient has not been established; use should be individualized.
PGT-M
PGT-M is designed for a known familial monogenic condition and usually requires case-specific test development, molecular confirmation and genetic counselling before the IVF cycle.
PGT-SR
PGT-SR is used when a parent carries a structural chromosome rearrangement associated with risk of unbalanced embryos.
Mosaic results
Mosaic embryo results require careful interpretation because a trophectoderm biopsy samples a small portion of the embryo and laboratory thresholds vary.
Clinical use note: This resource supports professional decision making but does not replace current specialty guidelines, multidisciplinary review, the validated scope of the exact laboratory assay, or patient-specific clinical judgement.
Planning PGT for a patient?
Our reproductive genetics team can support test selection, PGT-M work-up and counselling.